The study provides a unique opportunity with a proven Congolese partner to examine the combined and synergistic effects of two proven structural interventions; 1) Rabbits for Resilience (RFR), youth-led economic empowerment program; and 2) Indashyikirwa (IK), a couples/parents-based gender equality program on adolescent mental health. Using a clustered randomized controlled trial with three groups (RFR only, IK only, RFR + IK), we examine the combined and synergistic effects of the interventions and the pathways through which RFR and IK improves adolescent mental health.