Reactive vaccination campaigns aim to rapidly increase the population level of immunity and reduce the number of susceptible people who could be infected with the circulating disease, therefore reducing the spread of the pathogen. However, the implementation of reactive campaign faces a variety of challenges that delay or completely hinder their implementation. This study aims to identify key barriers and enablers to the implementation of reactive vaccination campaigns after an outbreak has been declared and formulate solutions to improve timeliness and implementation of such campaigns.